Self-Medication Administration for Hemophiliac
1) Wash your hands
2) Gather your supplies:
Factor to be infused
Butterfly (23-25G) for infusion
Tourniquet (should be supplied by
Gloves, if infused by someone other
than the patient.
Gauze and tape
3) Review vein selection, try to locate more than 1 vein, if possible.
Remember, locate on non-dominant side first, then locate on
4) Use hand sanitizer, don gloves (if needed), mix factor, then
prime Butterfly. Apply tourniquet, swab the area with alcohol
and air dry.
5) Access vein at an appropriate angle (shallow veins 15-30
degrees, deeper veins up to 45 degrees).
6) Once vein accessed, loosen tourniquet, slowly infuse Factor.
7) Remove Butterfly, apply gauze and tape.
Before you begin the mixing process, bring vials to room temperature. Wash your hands thoroughly, put on gloves, and always work on a clean, flat surface. Remove caps from the ADVATE [Antihemophilic Factor (Recombinant)] concentrate and water vials, then disinfect the stoppers with alcohol swabs and allow to dry.
Without touching the BAXJECT II device, peel away the lid of the package. After placing the vial on a hard, flat surface, invert the device over the water vial and press down until the CLEAR spike pierces the water vial stopper.
Grip the edge of the packaging to remove it from the device. Be sure not to touch the white spike or remove the blue cap. Invert the device with water vial attached, so that the water vial is now on top. Press the device down on the product vial until the white spike pierces the stopper. Wait for the water to enter the ADVATE vial, then swirl gently until the ADVATE is completely dissolved. Do not shake.
It is acceptable for a small amount of water to be left behind. If the water does not transfer successfully, please refer to the troubleshooting guide in the menu.
The ADVATE solution should look clear and colorless. If not, do not use it and notify Shire immediately.
Remove the blue cap from the device. Next, remove the syringe cap and connect the syringe to the device by screwing it onto the device. With the syringe attached, invert the device white side up so that the ADVATE vial is on top.
Now, slowly pull the plunger back on the syringe to withdraw the mixed product. If you find it impossible to withdraw some or all of the mixed product into the syringe, there may be air in the device. Please refer to the troubleshooting guide in the menu.
Finally, disconnect the syringe by unscrewing it. You are now ready to infuse the product. Do not refrigerate after reconstitution.